THE MECHANISM OF TRANSPLACENTAL ISOIMMUNIZATION

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Mechanisms of isoimmunization. II. Transplacental passage and postnatal survival of fetal erythrocytes in heterospecific pregnancies.

K NOWLEDGE CONCERNING the transpiacental passage of fetal erythrocytes into the maternal circulation is of critical importance for the understanding of immunologic relationships between mother and child and specifically for the mechanisms of Rh isoimmunization. In a previous study1 the phenomenon of transplacental passage was investigated in homospecific pregnancies-i.e., in the absence of mate...

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SIRy-Mr. W. L. Whitehouse (21 June, p. 759), like myself' and many others, again calls attention to the potential dangers of rhesus isoimmunization in therapeutic abortion. He asks that the extent of this problem be further and scientifically investigated. There are, in fact, one or two further facets to be considered. Firstly, all of us are aware of the numbers of women whose first continuing ...

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ژورنال

عنوان ژورنال: Blood

سال: 1948

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v3.4.404.404